Thermo Fisher Scientific FBXO11 Polyclonal Antibody
FBXO11 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ChIP assay에 적합합니다. Human 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS 기반 용액에 보관되며, -20°C에서 보관 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| ChIP assay (ChIP) | 0.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human FBXO11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606953 |
Product Specific Information
Peptide sequence:
HDVEFIRHDR FFCDCGAGTL SNPCTLAGEP THDTDTLYDS APPIESNTLQ
Sequence homology:
Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
FBXO11 is a member of the F-box protein family characterized by an approximately 40 amino acid F-box motif. These proteins form one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
The F-box proteins are divided into three classes:
- Fbws: containing WD-40 domains
- Fbls: containing leucine-rich repeats
- Fbxs: containing various protein-protein interaction modules or no recognizable motifs
The FBXO11 gene encodes a member of the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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