Thermo Fisher Scientific GLRX Polyclonal Antibody
GLRX 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 다양한 종에서 높은 상동성을 보여 연구용으로 활용도가 높습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 제공됩니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human GLRX (aa 30–79) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690484 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Guinea Pig: 83%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 100%; Rat: 93%; Sheep: 100%
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small, heat-stable oxidoreductase. Grxs are part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
Originally identified in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase reactions via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved across species. This 12-kDa dithiol protein plays a role in reducing mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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