Thermo Fisher Scientific Human SCUBE1 Synthetic Peptide

Thermo Fisher Scientific Human SCUBE1 Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 14 amino acids near the center of human SCUBE1.
PEP-1104 can be used as a blocking peptide with polyclonal antibody PA5-20990.

Target Information

SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm, and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca²⁺-dependent fashion.
The C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mouse embryos, suggesting SCUBE1 plays a role in brain morphogenesis.
SCUBE1 has also been implicated in early craniofacial development in mice.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.