
Thermo Fisher Scientific KLRG1 Monoclonal Antibody (2F1), PE
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Applications
Tested Dilution
Publications
Flow Cytometry (Flow)
0.1-0.2 µg / 1x10^6 cells
Product Specifications
Host/Isotype
Syrian hamster / IgG
Class
Monoclonal
Type
Antibody
Clone
2F1
Immunogen
Activated NK (A-LAK) cells from B6 (H-2b) mice.
Conjugate
PE PE PE
View additional formats
Excitation/Emission Max
565/576 nm View spectra
Form
Liquid
Concentration
0.1 mg/mL
Storage conditions
4° C
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
RRID
AB_2536604
Target Information
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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