Thermo Fisher Scientific Human MFSD2A Synthetic Peptide
Human MFSD2A 단백질의 C-말단 18개 아미노산 서열을 기반으로 한 합성 펩타이드. MFSD2A 항체의 블로킹 실험에 사용 가능. 고순도 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP1163
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human MFSD2A Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human MFSD2A.
PEP-1163 can be used as a blocking peptide with polyclonal antibody PA5-21049.
Target Information
Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs.
Major Facilitator Superfamily (MFS) members transport various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific.
MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts.
MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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