Thermo Fisher Scientific Human MFSD2A Synthetic Peptide

Thermo Fisher Scientific Human MFSD2A Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 18 amino acids near the carboxy terminus of human MFSD2A.
PEP-1163 can be used as a blocking peptide with polyclonal antibody PA5-21049.

Target Information

Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs.
Major Facilitator Superfamily (MFS) members transport various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific.
MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts.
MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.

Notes

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.