Thermo Fisher Scientific C1QB/Complement C1q B-Chain Monoclonal Antibody (C1QB, 2966)
인간 C1QB 단백질을 인식하는 mouse monoclonal antibody로 면역조직화학(IHC) 및 펩타이드 어레이 분석에 적합. Protein A/G 정제 및 PBS buffer에 보존, 보존제 무첨가. C1q 관련 연구 및 루푸스, 신장염 연구에 활용 가능.
- 카탈로그번호
- 713-MSM6-P1ABX
- 판매단위
- pk
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Thermo Fisher Scientific C1QB/Complement C1q B-Chain Monoclonal Antibody (C1QB, 2966)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1QB, 2966 |
| Immunogen | Recombinant fragment (around aa 41–188) of human C1QB protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
C1QB is a major constituent of the human complement subcomponent C1q.
C1q associates with C1r and C1s to form the first component of the serum complement system.
Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.
C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains.
Each chain contains a collagen-like region near the N terminus and a C-terminal globular region.
The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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