Thermo Fisher Scientific FOLH1 Monoclonal Antibody (OTI2E1), TrueMAB
FOLH1 단백질을 표적으로 하는 마우스 단클론 항체로, WB, ICC/IF, ELISA 등에 사용 가능. 인간, 개, 생쥐, 랫드 반응성. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용 진단 마커 및 단백질 기능 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E1 |
| Immunogen | Full length human recombinant protein of human FOLH1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The FOLH1 gene encodes a type II transmembrane glycoprotein of the M28 peptidase family.
This protein functions as a glutamate carboxypeptidase on substrates such as folate and N-acetyl-L-aspartyl-L-glutamate.
It is expressed in tissues including the prostate, central and peripheral nervous system, and kidney.
Mutations may lead to impaired folate absorption and hyperhomocysteinemia.
In the prostate, FOLH1 is up-regulated in cancerous cells and serves as a diagnostic and prognostic marker for prostate cancer.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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