Thermo Fisher Scientific SUV420H1 Polyclonal Antibody
Thermo Fisher Scientific의 SUV420H1 폴리클로날 항체는 Western blot 및 ChIP assay에 사용 가능합니다. 인간 SUV420H1 중간 영역 펩타이드를 면역원으로 제작되었습니다. 다양한 종에 반응하며, 액상 형태로 제공되어 안정적인 실험 결과를 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SUV420H1 (aa 271–320) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689479 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 77%; Rat: 100%; Zebrafish: 77%
Target Information
Histone methyltransferase that specifically trimethylates Lys-20 of histone H4.
H4 Lys-20 trimethylation represents a specific tag for epigenetic transcriptional repression.
Mainly functions in pericentric heterochromatin regions, thereby playing a central role in establishing constitutive heterochromatin in these regions.
KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1, and RBL2).
Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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