Thermo Fisher Scientific EMB Monoclonal Antibody (3F12)
EMB 단백질을 표적으로 하는 Thermo Fisher Scientific의 3F12 마우스 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 반응성, 액상 형태, 친화 크로마토그래피 정제, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific EMB Monoclonal Antibody (3F12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F12 |
| Immunogen | EMB (NP_940851.1, 1–327 a.a) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MRALPGLLEA RARTPRLLLL QCLLAAARPS SADGSAPDSP FTSPPLREEI MANNFSLESH NISLTEHSSM PVEKNITLER PSNVNLTCQF TTSGDLNAVN VTWKKDGEQL ENNYLVSATG STLYTQYRFT IINSKQMGSY SCFFREEKEQ RGTFNFKVPE LHGKNKPLIS YVGDSTVLTC KCQNCFPLNW TWYSSNGSVK VPVGVQMNKY VINGTYANET KLKITQLLEE DGESYWCRAL FQLGESEEHI ELVVLSYLVP LKPFLVIVAE VILLVATILL CEKYTQKKKK HSDEGKEFEQ IEQLKSDDSN GIENNVPRHR KNESLGQ
Target Information
Embigin is a 327 amino acid regulatory protein belonging to the immunoglobulin superfamily class of CAMs, with two Ig-like V-type domains.
In situ hybridization analysis shows that Embigin has specific carbohydrate epitopes and plays an important role in early postimplantation embryogenesis.
It is a highly glycosylated transmembrane glycoprotein acting as a regulator of cell/ECM interactions during development and homeostasis of normal adult tissues.
Transfection studies suggest its role in promotion of integrin-mediated cell-substratum adhesion.
Widely expressed in most tissues and embryonal carcinoma cells, prostate and mammary cancer cell lines, it may also assist in the classification of human carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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