Thermo Fisher Scientific TRPC3 Polyclonal Antibody
TRPC3 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에 반응합니다. Western blot, IHC, ELISA 등에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1.0–2.0 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL | |
| ELISA | Assay-Dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 19 amino acid peptide from near the carboxy terminus of human TRPC3 (amino acids 710–760) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718728 |
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family. The seven members of this family share activation through PLC-coupled receptors and are suggested to be components of receptor-regulated cation channels in various cell types. The TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, indicating a possible activation mechanism via PLC-coupled receptors.
TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 interacts with TRPC6 and TRPC7 to form functional tetrameric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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