Thermo Fisher Scientific Cyclin F Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from the date of receipt.

Target Information

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases.
This member also belongs to the F-box protein family, characterized by an approximately 40 amino acid motif, the F-box.
The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
The F-box proteins are divided into three classes:

• Fbws containing WD-40 domains
• Fbls containing leucine-rich repeats
• Fbxs containing either different protein-protein interaction modules or no recognizable motifs

The protein encoded by this gene belongs to the Fbxs class and was one of the first proteins in which the F-box motif was identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.