Thermo Fisher Scientific SMARCA1 Polyclonal Antibody
SMARCA1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. 인간 시료 반응성, 액상 형태, 친화 크로마토그래피 정제, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–200 of human SMARCA1 (NP_0030602) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.40 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804381 |
Product Specific Information
- Immunogen sequence:
MEQDTAAVAA TVAAADATAT IVVIEDEQPG PSTSQEEGAA AAATEATAAT EKGEKKKEKN VSSFQLKLAA KAPKSEKEMD PEYEEKMKAD RAKRFEFLLK QTELFAHFIQ PSAQKSPTSP LNMKLGRPRI KKDEKQSLIS AGDYRHRRTE QEEDEELLSE SRKTSNVCIR FEVSPSYVKG GPLRDYQIRG LNWLISLYEN - Positive Samples: HeLa, 293T, A-549, HT-1080, LO2
- Cellular Location: Nucleus
Target Information
Members of this G protein family are characterized by the presence of conserved SNF2 domain, a helicase-like region. They also have ATPase activity and are thought to play a significant role in regulating chromatin remodeling. Although SNF2L1 has a ubiquitous expression pattern, its active form is expressed in neurons, suggesting a role in promoting neurite outgrowth and regulating neuronal physiology.
Principal Names: SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 1 (SMARCA1); SNF2L1; SNF2LB; Possible global transcription activator SNF2L1; SWI2
Official Gene Symbol: SMARCA1
GenBank Accession Number: NP_620604
Gene ID: 6594 (Human)
Gene Map Locus: Xq25 (Human)
Protein: SNF2L1, ~123 kDa, member of SWI/SNF family of proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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