Thermo Fisher Scientific ZHX2 Recombinant Rabbit Monoclonal Antibody (8N7O2)
Thermo Fisher Scientific의 ZHX2 Recombinant Rabbit Monoclonal Antibody (8N7O2)은 인간 및 마우스 시료에 반응하며, WB와 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 단클론 항체로, 높은 순도와 안정성을 제공하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8N7O2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 260–500 of human ZHX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
VPLNTTKYNS ALDTNATMIN SFNKFPYPTQ AELSWLTAAS KHPEEHIRIW FATQRLKHGI SWSPEEVEEA RKKMFNGTIQ SVPPTITVLP AQLAPTKVTQ PILQTALPCQ ILGQTSLVLT QVTSGSTTVS CSPITLAVAG VTNHGQKRPL VTPQAAPEPK RPHIAQVPEP PPKVANPPLT PASDRKKTKE QIAHLKASFL QSQFPDDAEV YRLIEVTGLA RSEIKKWFSD HRYRCQRGIV H
Target Information
Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA).
ZHX1–3 are ubiquitously expressed proteins found in various tissues, acting as transcriptional repressors localized in the nucleus.
These proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs), enabling homodimer and heterodimer formation.
Dimerization is not required for repressor activity.
Hypermethylation-mediated silencing of ZHX2 is an epigenetic event associated with hepatocellular carcinoma (HCC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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