Thermo Fisher Scientific TLR9 Monoclonal Antibody (5B10E8)
TLR9 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western blot, Flow cytometry, ELISA에 적합합니다. 인간 시료에 반응하며 Protein G로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B10E8 |
| Immunogen | Purified recombinant fragment of human CD289 (AA: extra 26–193) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090761 |
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
They recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immunity.
TLR9 is preferentially expressed in immune cell–rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes.
Studies in mice and humans indicate that this receptor mediates cellular responses to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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