Thermo Fisher Scientific KCTD11 Polyclonal Antibody
Thermo Fisher Scientific의 KCTD11 Polyclonal Antibody는 인간 KCTD11 단백질을 인식하는 염소 유래 IgG 항체로, Western blot 및 Peptide ELISA에 적합합니다. 고순도(암모늄 황산 침전)로 정제되어 있으며, 안정적인 액상 형태로 TBS 버퍼 내 보존됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PEVEYGRLGLQP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933272 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
Calponin is a thin filament-associated protein involved in the regulation and modulation of smooth muscle contraction. It binds to actin, calmodulin, troponin C, and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle.
Two isoforms exist:
- 34 kDa form
- 29 kDa form (primarily in urogenital tract muscle)
Calponin expression is also observed in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes, and nerve fibers, aiding differentiation of breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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