Thermo Fisher Scientific XPA Polyclonal Antibody
인간 XPA 단백질에 특이적인 Rabbit Polyclonal Antibody로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS 기반 용액 형태로, 단기 4°C·장기 -20°C 보관 가능. 연구용으로만 사용.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human XPA (Product #RP-106734) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2791467 |
Product Specific Information
Immunogen sequence:
FMDSYLMNHF DLPTCDNCRD ADDKHKLITK TEAKQEYLLK DCDLEKREPP LKFIVKKNPH HSQWGDMKLY LKLQIVKRSL EV
Target Information
The XPA (xeroderma pigmentosum group A) protein specifically recognizes UV- or chemically damaged DNA lesions and triggers the nucleotide excision repair process.
XPA binds to replication protein A (RPA) or excision repair cross complementing 1 protein (ERCC1).
In the absence of nucleotide excision repair, persisting unrepaired DNA lesions may lead to gene mutations and ultimately to cancer.
Xeroderma pigmentosum patients have a >2000-fold increased risk of developing skin cancer at sun-exposed areas.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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