Thermo Fisher Scientific Human TFPI Synthetic Peptide
인간 TFPI의 N-말단 13개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-34578의 블로킹 펩타이드로 사용 가능. 액상 형태로 제공되며 PBS(pH 7.2, 0.1% BSA) 완충액에 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the amino terminus of TFPI.
PEP-1621 can be used as a blocking peptide with polyclonal antibody PA5-34578.
For Western blot blocking, incubate the peptide with an equal volume of antibody for 30 minutes at 37°C.
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma, both in free forms and complexed with plasma lipoproteins.
The coagulation process begins with the formation of a factor VIIa-TF complex, which activates additional proteases (factors IX and X), ultimately leading to fibrin clot formation. TFPI inhibits activated factor X and VIIa-TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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