Thermo Fisher Scientific Mimecan Polyclonal Antibody
Thermo Fisher Scientific의 Mimecan Polyclonal Antibody는 인간 Mimecan 단백질에 특이적으로 반응하는 Rabbit IgG 항체로, IHC, ICC/IF 등 다양한 응용에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 연구용에 적합합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Mimecan. Recombinant protein control fragment (Product #RP-89834) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643974 |
Product Specific Information
Immunogen sequence:
SLLEELSLAE NQLLKLPVLP PKLTLFNAKY NKIKSRGIKA NAFKKLNNLT FLYLDHNALE SVPLNLPESL RVIHLQFNNI ASITDDTFCK ANDTSYIRDR IEEIRLEGNP IVLGKHPNSF I
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 88%
Target Information
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan containing tandem leucine-rich repeats and is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family. It may regulate osteoblast differentiation and is associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants encoding mimecan.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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