Thermo Fisher Scientific CD1C Monoclonal Antibody (OTI1F4), TrueMAB
인간 CD1C 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제 및 PBS/BSA/glycerol 저장. 비결합형 포맷으로 다양한 컨주게이션 옵션 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F4 |
| Immunogen | Full length human recombinant protein of human CD1C produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The CD1C gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins, and forms heterodimers with beta-2-microglobulin. CD1 proteins mediate the presentation of lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes located on chromosome 1. These members differ in localization and lipid ligand specificity. The CD1C protein localizes to late endosomes and lysosomes via a tyrosine-based motif in its cytoplasmic tail and requires vesicular acidification for lipid antigen binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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