Thermo Fisher Scientific UGT8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UGT8. Recombinant protein control fragment (Product #RP-90684). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UGT8,uniProtId:Q16880-1,ncbiNodeId:9606,antigenRange:43-172,antigenLength:541,antigenImageFileName:PA5-53160_UGT8_Q16880-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53160_UGT8_Q16880-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649253

Product Specific Information

Immunogen sequence: SALHERGHHT VFLLSEGRDI APSNHYSLQR YPGIFNSTTS DAFLQSKMRN IFSGRLTAIE LFDILDHYTK NCDLMVGNHA LIQGLKKEKF DLLLVDPNDM CGFVIAHLLG VKYAVFSTGL WYPAEVGAPA

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Target Information

UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single pass membrane protein of the UDP-glycosyltransferase family. UGT8 is believed to be primarily involved with the metabolism of sphingolipids and galactosylceramide biosynthesis. UGT8 is one of six genes whose elevated expression has been correlated with a significantly increased the risk of lung metastases in breast cancer patients. As such, UGT8 may be a significant index of tumor aggressiveness and a potential marker for the prognostic evaluation of lung metastases in breast cancer. UGT8 is ubiquitously expressed with highest levels found in central and peripheral nervous systems and is up-regulated in breast cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.