Thermo Fisher Scientific AMPK alpha-2 Polyclonal Antibody, Biotin
AMPK alpha-2 단백질을 인식하는 염소 폴리클로날 항체로, Biotin으로 표지되어 있습니다. Western blot에 적합하며 인간 시료에 반응합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS 버퍼(pH 7.3)와 BSA를 포함합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence CPLDALNTTKP (aa 382–392) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2933248 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. It functions as a key energy-sensing enzyme that monitors cellular energy status. Upon metabolic stress, AMPK becomes activated and phosphorylates enzymes such as acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), thereby regulating fatty acid and cholesterol biosynthesis. Studies in mice suggest that this subunit is essential for maintaining insulin sensitivity and myocardial energy homeostasis during ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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