Thermo Fisher Scientific LYL1 Polyclonal Antibody
LYL1 단백질을 검출하기 위한 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Recommended positive control: K562
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 169–280 of LYL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| RRID | AB_2553226 |
Product Specific Information
- Recommended positive control: K562
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Lyl-1, TAL1, and TAL2 belong to a family of basic helix-loop-helix (bHLH) proteins implicated in T-cell acute leukemia.
TAL1 (SCL) is a serine phosphoprotein and transcription factor regulating embryonic hematopoiesis.
TAL2 is involved in T-cell acute lymphoblastic leukemia through a chromosomal translocation involving TAL2 and TCR β genes.
Lyl-1 (lymphoblastic leukemia-derived sequence 1) is a nuclear protein forming complexes with E2α proteins, exhibiting distinctive DNA-binding properties in hematolymphoid cells.
Lyl-1 is associated with chromosomal aberrations causing T-cell acute lymphoblastic leukemia (T-ALL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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