Thermo Fisher Scientific GFR alpha-2 Recombinant Rabbit Monoclonal Antibody (104)
Recombinant rabbit monoclonal antibody recognizing human GFRA2. Validated for Western blot. Provides high specificity, sensitivity, and lot-to-lot consistency. Preservative-free liquid form, stored refrigerated or frozen for long-term use.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 104 |
| Immunogen | Recombinant Human GFRA2 protein (Met1–Ser441) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2785181 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human GFRA2.
Target Information
GFRα-2 binds NTN and mediates activation of the RET receptor tyrosine kinase by both NTN and GDNF. NTN, GFRα-2, and the RET PTK form a complex to transduce NTN signals and mediate NTN functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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