Thermo Fisher Scientific NMI Monoclonal Antibody (OTI2C1)
NMI 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 시료에 반응하며, Affinity Chromatography로 정제됨. PBS/BSA/glycerol buffer에 보관되며, -20°C에서 보관 권장. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–223 of NMI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724846 |
Target Information
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif.
The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma.
NMI mRNA has low expression levels in most human fetal and adult tissues except brain and shows high expression in myeloid leukemia cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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