Thermo Fisher Scientific CCT3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CCT3, suitable for WB, IHC, and IP applications. Recognizes region 300–350 of CCT3. Predicted to react with Rat and Orangutan. Supplied as liquid, unconjugated, 0.20 mg/mL concentration, stored at 4°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 350 of human Chaperonin containing TCP1, Subunit 3 (CCT3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Orangutan
Target Information
The protein encoded by this gene is a molecular chaperone and a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC).
This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner.
The complex folds various proteins including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene, and a pseudogene has been found on chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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