Thermo Fisher Scientific ETV4 Monoclonal Antibody (OTI5C11), TrueMAB
ETV4 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–276 of human ETV4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ETV4 (E1A enhancer binding protein, E1AF), also known as PEA3, belongs to the Ets gene family encoding sequence-specific DNA-binding proteins. Members include PU.1, Ets-1, Ets-2, and Fli-1. These proteins recognize DNA motifs containing a central 5'-GGAA-3' element. PEA3 binds specifically to the motif 5'-AGGAAG-3' but not 5'-AGGAAC-3', which is recognized by PU.1. While all Ets proteins share this core recognition sequence, each interacts with unique flanking sequences. PEA3 is expressed in epithelial and fibroblastic cells but not in hematopoietic cells, unlike other Ets family members such as Ets-1, Ets-2, and Fli-1, which are expressed mainly in hematopoietic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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