Thermo Fisher Scientific WDR5 Monoclonal Antibody (2C2)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2C2

Immunogen

WDR5 (NP_060058, 16 a.a. approximately 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WDR5,uniProtId:P61964-1,ncbiNodeId:9606,antigenRange:16-120,antigenLength:334,antigenImageFileName:H00011091-M01J_WDR5_P61964-1_House_mouse.svg,antigenImageFileNamePDP:H00011091-M01J_WDR5_P61964-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: QPTPSSSATQ SKPTPVKPNY ALKFTLAGHT KAVSSVKFSP NGEWLASSSA DKLIKIWGAY DGKFEKTISG HKLGISDVAW SSDSNLLVSA SDDKTLKIWD VSSGK

Target Information

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.