Thermo Fisher Scientific OLIG2 Polyclonal Antibody
OLIG2 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 인간 Olig-2 C-말단 합성 펩타이드로 면역화됨. 보존제 무첨가이며 냉장 또는 냉동 보관 권장. 연구용으로만 사용.
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- PA580871
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Thermo Fisher Scientific OLIG2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:1,500–1:50,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of Human Olig-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Refrigerate at 2–8°C for up to 1 month. For long-term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788136 |
Product Specific Information
- Preservative free formulation.
- Recommended to add sodium azide to prevent contamination (final concentration 0.05%–0.1%).
- Specificity: Human Olig-2.
Target Information
OLIG2 encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. It is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Located on chromosome 21, it may contribute to learning deficits in Down syndrome.
Tissue Specificity:
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas; weak to moderate expression in astrocytomas; variable expression in glioblastomas.
Note: For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지: PA5-80871_OLIG2_Q13516-1_Rabbit.svg)
(이미지: PA5-80871_OLIG2_Q13516-1_Rabbit_PDP.jpeg)
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