Thermo Fisher Scientific NIT1 Monoclonal Antibody (OTI4D12), TrueMAB
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
1:50
Immunocytochemistry (ICC/IF)
1:100
Flow Cytometry (Flow)
1:100
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4D12
Immunogen
Full length human recombinant protein of human NIT1 produced in HEK293T cell. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
NIT1,
uniProtId:
Q86X76-1,
ncbiNodeId:
9606,
antigenRange:
1-327,
antigenLength:
327,
antigenImageFileName:
TA501034_NIT1_Q86X76-1_House_mouse.svg,
antigenImageFileNamePDP:
TA501034_NIT1_Q86X76-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.66 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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