Thermo Fisher Scientific FASN Monoclonal Antibody (GT556)
FASN 단백질을 인식하는 Mouse monoclonal antibody (Clone GT556). Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat에 반응. Protein G 정제, PBS buffer, preservative-free. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT556 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787122 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (89%), Rat (89%), Pig (83%), Bovine (85%).
- Positive Control: 293T, A431, HeLa, HepG2.
- Centrifuge briefly prior to opening the vial.
Target Information
Fatty acid synthase is a multifunctional protein responsible for catalyzing the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, producing long-chain saturated fatty acids.
In certain cancer cell lines, FASN has been reported to fuse with estrogen receptor-alpha (ER-alpha), resulting in an in-frame fusion between the N-terminus of FAS and the C-terminus of ER-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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