Thermo Fisher Scientific RAD51 Polyclonal Antibody
인간 RAD51 단백질을 인식하는 토끼 폴리클로날 항체로, DNA 복구 연구에 적합합니다. IHC 및 ICC/IF에 사용 가능하며, 보존제가 없는 고순도 항체입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific RAD51 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human RAD51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788473 |
Product Specific Information
- This product is preservative-free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human RAD51.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recombination.
It binds to single- and double-stranded DNA and exhibits DNA-dependent ATPase activity.
RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template.
It binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments essential for the homology search and strand exchange.
Mutations in the RAD51 gene can result in breast cancer, mirror movements 2, and Fanconi anemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-81248_RAD51_Q06609-1_Rabbit.svg, PA5-81248_RAD51_Q06609-1_Rabbit_PDP.jpeg)
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