Thermo Fisher Scientific NMBR Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMBR (neuromedin B receptor). Validated for IHC (paraffin) at 9 µg/mL. Antigen affinity purified, supplied in PBS with 0.1% sodium azide. Suitable for detecting NMBR expression in various human tissues and can...
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Applications
Tested Application and Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 9 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from C-terminus of human NMBR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551337 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon: 100%
- Monkey, Marmoset, Mouse, Elephant, Bovine: 89%
- Rat, Panda, Dog, Bat, Rabbit, Pig, Platypus: 84%
Target Information
NMBR (Neuromedin B Receptor) is a Bombesin receptor that activates phospholipase and protein kinase C, enhancing calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and gastrointestinal epithelial tissues.
Expression of NMBR has been reported in:
- Brain (olfactory bulb, thalamus)
- Colon, liver, placenta, testis, spinal cord, and gastrointestinal tract
- Cancers of lung, ovary, and prostate
ESTs have been isolated from B-cell, lung, testis, and brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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