Thermo Fisher Scientific ESRP1 Polyclonal Antibody
ESRP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 생쥐 시료에 반응하며 Western blot에 적합. 액상 형태로 제공되며 PBS와 50% glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ESRP1 (Accession Q6NXG1), corresponding to amino acid residues K514–A564 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2899836 |
Product Specific Information
Antibody detects endogenous levels of total ESRP1.
Target Information
RBM35A, also known as ESRP1, is an mRNA splicing factor that, along with its related protein RBM35B (ESRP2), coordinates an epithelial cell-type-specific splicing program.
RBM35A contains three putative RNA recognition motifs and binds specific sequences in mRNAs. It regulates posttranscriptional expression of genes such as FGFR2, CD44, CTNND1, and ENAH, affecting protein translation via 5′ UTR regions.
Recent studies suggest that RBM35A may function as a novel tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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