Thermo Fisher Scientific ERCC2 Monoclonal Antibody (4G2-2A6)
ERCC2 단백질을 표적으로 하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4G2-2A6). Western blot 및 ELISA에 적합하며, 인간 시료 반응성. Affinity chromatography로 정제된 액상 형태, PBS buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G2-2A6 |
| Immunogen | ERCC2 (AAH08346, 1–405 a.a.) full-length recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MRELKRTLDA KGHGVLEMPS GTGKTVSLLA LIMAYQRAYP LEVTKLIYCS RTVPEIEKVI EELRKLLNFY EKQEGEKLPF LGLALSSRKN LCIHPEVTPL RFGKDVDGKC HSLTASYVRA QYQHDTSLPH CRFYEEFDAH GREVPLPAGI YNLDDLKALG RRQGWCPYFL ARYSILHANV VVYSYHYLLD PKIADLVSKE LARKAVVVFD EAHNIDNVCI DSMSVNLTRR TLDRCQGNLE TLQKTVLRIK ETDEQRLRDE YRRLVEGLRE ASAARETDAH LANPVLPDEV LQEAVPGSIR TAEHFLGFLR RLLEYVKWRL RVQHVVQESP PAFLSGLAQR VCIQRKPLRF CAERLRSLLH TLEITDLADF SPLTLLANFA TLVSTYAKGQ AQHCGSSRNQ KRSHP
Target Information
XPD is involved in the nucleotide excision repair pathway, a mechanism to repair DNA damage. The encoded protein participates in transcription-coupled nucleotide excision repair and is a core component of the basal transcription factor BTF2/TFIIH complex. It exhibits ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Mutations in this gene are associated with xeroderma pigmentosum group D, trichothiodystrophy, and Cockayne syndrome. Alternative splicing results in multiple isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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