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Thermo Fisher Scientific 53BP1 Polyclonal Antibody
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Rabbit polyclonal antibody targeting human 53BP1 protein for WB, IHC, and IP applications. Recognizes residues 350–400 of 53BP1. Supplied as unconjugated liquid at 1 mg/mL, stored at 4°C, shipped on wet ice. For research use only.
- 카탈로그번호
- A300272Ax (2개 옵션)
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 01. 오후 11:39
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific A300272AM 53BP1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
477,300원VAT 포함 525,030원
Thermo Fisher Scientific A300272AT 53BP1 Polyclonal Antibody 10 ul pk판매 단위 pk ·
재고 확인 필요
194,600원VAT 포함 214,060원
Thermo Fisher Scientific · Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 350–400 of human tumor protein p53 binding protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to sites of double-strand breaks. It may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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