Thermo Fisher Scientific SND1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 26-285 of human SND1 (NP_0552052) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SND1,uniProtId:Q7KZF4-1,ncbiNodeId:9606,antigenRange:26-285,antigenLength:910,antigenImageFileName:PA5-89222_SND1_Q7KZF4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89222_SND1_Q7KZF4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805427

Product Specific Information

Immunogen sequence: MVLSGCAIIV RGQPRGGPPP ERQINLSNIR AGNLARRAAA TQPDAKDTPD EPWAFPAREF LRKKLIGKEV CFTIENKTPQ GREYGMIYLG KDTNGENIAE SLVAEGLATR REGMRANNPE QNRLSECEEQ AKAAKKGMWS EGNGSHTIRD LKYTIENPRH FVDSHHQKPV NAIIEHVRDG SVVRALLLPD YYLVTVMLSG IKCPTFRREA DGSETPEPFA AEAKFFTESR LLQRDVQIIL ESCHNQNILG TILHPNGNIT; Positive Samples: HeLa, Jurkat, HL-60, MCF7, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Melanosome, Nucleus

Target Information

SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.