Thermo Fisher Scientific BCL11A Polyclonal Antibody
Rabbit polyclonal antibody targeting human BCL11A protein. Recombinant protein immunogen-based, unconjugated liquid form. Suitable for research use in hematopoietic and lymphoma studies. Stored at 4°C short term or -20°C long term.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCL11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790204 |
Product Specific Information
Immunogen sequence:
LSTASSPEPG TSDLVGSASS ALKSVVAKFK SENDPNLIPE NGDEEEEEDD EEEEEEEEEE EEELTESERV DYGFGLSL
Target Information
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulate its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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