Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI12C12), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

For reconstitution, it is recommended to add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines through phosphorylation by MAP kinase kinases or autophosphorylation via MAP3K7IP1/TAB1 interaction.
Substrates include transcription regulators (ATF2, MEF2C, MAX), cell cycle regulator (CDC25B), and tumor suppressor (p53), indicating its roles in stress-related transcription, cell cycle regulation, and genotoxic stress response.
Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.