Thermo Fisher Scientific SH3PXD2A Polyclonal Antibody
SH3PXD2A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 항체로 Human, Mouse, Rat 시료에 반응. Antigen affinity chromatography로 정제되어 높은 특이성과 안정성 제공. 연구용으로만 사용.
- 카탈로그번호
- PA558169
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SH3PXD2A. Recombinant protein control fragment (Product #RP-97054). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647251 |
Product Specific Information
Immunogen sequence:
PDPSGKELDT VPAKGRQNEG KSDSLEKIER RVQALNTVNQ SKKATPPIPS KPPGGFGKTS GTPAVKMRNG VRQVAVRPQS VFVSP
Sequence Identity:
- Mouse: 86%
- Rat: 88%
Target Information
Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation, and invasiveness of some cancer cells.
Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs), and phosphoinositides.
Acts as an organizer protein enabling NOX1- or NOX3-dependent ROS generation and localization.
In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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