Thermo Fisher Scientific ATP6V1C2 Polyclonal Antibody
Human ATP6V1C2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보존. 세포 내 소기관 산성화 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATP6V1C2. Recombinant protein control fragment (Product #RP-108526) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791904 |
Product Specific Information
Immunogen sequence:
YPVKQPLVSV VDTIAKQLAQ IEMDLKSRTA AYNTLKTNLE NLEKKSMGNL FTRTLSDIVS KED
Target Information
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase–dependent organelle acidification is essential for processes such as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.
V-ATPase consists of a cytosolic V1 domain and a transmembrane V0 domain.
The V1 domain contains three A, three B, and two G subunits, as well as C, D, E, F, and H subunits, and includes the ATP catalytic site.
This gene produces alternate splice variants encoding different V1 domain C subunit isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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