Thermo Fisher Scientific ABHD12 Polyclonal Antibody
ABHD12 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관, -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABHD12. Recombinant protein control fragment (Product #RP-90030) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637548 |
Product Specific Information
Immunogen sequence:
ALILESPFTN IREEAKSHPF SVIYRYFPGF DWFFLDPITS SGIKFANDEN VKHISCPLLI LHAEDDPVVP FQLGRKLYSI AAPARSFRDF KVQFVPFHSD LGYRHKYIYK SPELPRILRP
- Highest antigen sequence identity to orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors CB1 and CB2.
The endocannabinoid system is involved in various physiological processes including neurotransmission, mood, appetite, pain perception, addiction behavior, and inflammation.
Mutations in this gene are associated with the neurodegenerative disease PHARC, resulting from an inborn error of endocannabinoid metabolism.
Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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