Thermo Fisher Scientific ABHD12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ABHD12. Recombinant protein control fragment (Product #RP-90030).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637548

Product Specific Information

Immunogen sequence: ALILESPFTN IREEAKSHPF SVIYRYFPGF DWFFLDPITS SGIKFANDEN VKHISCPLLI LHAEDDPVVP FQLGRKLYSI AAPARSFRDF KVQFVPFHSD LGYRHKYIYK SPELPRILRP

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Target Information

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.