Thermo Fisher Scientific CBX7 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.

Target Information

The protein encoded by the CBX7 gene is a subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in promoter regions of various genes.
Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds DNA with high specificity and affinity.
The A subunit mediates sequence-specific interactions, acting as the regulatory component.
Post-transcriptional regulation occurs through protein degradation or translational control, and alternative splicing in the glutamine-rich activation domain leads to tissue-specific isoforms.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.