Thermo Fisher Scientific CBX7 Polyclonal Antibody
CBX7 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, IP 등 다양한 응용에 적합합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 인간 CBX7의 201–251번 아미노산 영역을 면역원으로 제작되었습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 5–15 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 201 and 251 of human chromobox homolog 7 (CBX7, UniProt ID: O95931-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
The protein encoded by the CBX7 gene is a subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in promoter regions of various genes.
Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds DNA with high specificity and affinity.
The A subunit mediates sequence-specific interactions, acting as the regulatory component.
Post-transcriptional regulation occurs through protein degradation or translational control, and alternative splicing in the glutamine-rich activation domain leads to tissue-specific isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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