Thermo Fisher Scientific TFPI Monoclonal Antibody (1#)
TFPI 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 IHC(P) 검증 완료. Recombinant TFPI(aa 29-302)를 면역원으로 제작. 단백질 정제는 Protein A/G 방식이며, PBS+50% glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1# |
| Immunogen | Recombinant protein Tissue Factor Pathway Inhibitor (TFPI), corresponding to amino acid range 29–302 of the target protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899162 |
Target Information
Tissue Factor Pathway Inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process begins with the formation of a factor VIIa–TF complex, which activates additional proteases (factors IX and X) leading to fibrin clot formation. TFPI inhibits activated factor X and VIIa–TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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