Thermo Fisher Scientific Chromogranin A Polyclonal Antibody
Rabbit polyclonal antibody against human Chromogranin A. Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제. 신경내분비 종양 및 카르시노이드 종양 표지 연구에 유용. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5110826
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Chromogranin A (Product #RP-96603) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856237 |
Product Specific Information
Immunogen sequence:
NSPMNKGDTE VMKCIVEVIS DTLSKPSPMP VSQECFETLR GDERILSILR HQNLLKELQD LALQGAKERA HQQKKHSGFE DELSEVLENQ SSQAELKEAV EEPSSKDVME KREDSKEAEK SGEATDGARP QALPEPMQES K
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells.
CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.
CHGA is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of Chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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