Thermo Fisher Scientific CD94 Monoclonal Antibody (18d3), FITC, eBioscience

Thermo Fisher Scientific CD94 Monoclonal Antibody (18d3), FITC, eBioscience™

Applications

• Flow Cytometry (Flow)

Tested Dilution: 0.5 µg/test
Publications: View 9 publications

Product Specifications

Additional Formats

• eFluor 450
• PE
• Request custom conjugation

Product Specific Information

The 18d3 monoclonal antibody reacts with mouse CD94, a 70 kDa type II transmembrane glycoprotein. CD94 belongs to the C-type lectin superfamily and forms a heterodimer with NKG2 on the cell surface. It is expressed by NK cells, subsets of T cells, and NKT cells, playing a key role in adhesion and activation of NK lineage cells. DBA/2J mice lack CD94 and do not express CD94/NKG2A receptors.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse splenocytes at ≤0.5 µg/test (100 µL final volume). Recommended to titrate for optimal performance.

Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered

Target Information

Natural killer (NK) cells expressing CD94 are lymphocytes that mediate cytotoxic activity and cytokine secretion upon immune stimulation. CD94 (KLRD1) is a type II membrane protein preferentially expressed on NK cells and associated with NKG2 family members. Three transcript variants encoding two isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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