Thermo Fisher Scientific SRSF11 Polyclonal Antibody
SRSF11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간과 생쥐 시료 반응성. 항원 친화 크로마토그래피로 정제된 액상 포맷, 안정적인 PBS/glycerol 버퍼 보관.
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Applications
- Western Blot (WB): 1:500–1:3,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human SFRS11 (UniProt ID: Q05519-1, antigen range: 452–478, antigen length: 484) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635595 |
Product Specific Information
This antibody detects endogenous levels of total SFRS11 protein.
Target Information
Pre-mRNA splicing enhancer elements activate weak splice sites essential for accurate splice site recognition and alternative splicing control. These elements bind SR-rich splicing factors such as SC35, 9G8, SRp20, and SF2/ASF.
SR factors possess RNA recognition motifs (RRM) and SR-rich domains, playing key roles in constitutive and alternative splicing regulation.
SFRS11 (splicing factor, arginine/serine-rich 11), also known as p54 or NET2, is a 484-amino-acid nuclear protein that colocalizes with spliceosome components and belongs to the SR family. It may function in pre-mRNA splicing and contains one RRM domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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