Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Thermo Fisher Scientific의 hnRNP D Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 hnRNP D 단백질 검출에 적합한 항체입니다. Western blot, IHC, ICC, ELISA, IP에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 액상 형태로 -20°C에서 보관합니다.
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Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing sequence corresponding to amino acids 1–306 of human HNRNPD (NP_002129.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806147 |
Product Specific Information
Immunogen sequence:
MSEEQFGGDG AAAAATAAVG GSAGEQEGAM VAATQGAAAA AGSGAGTGGG TASGGTEGGS AESEGAKIDA SKNEEDEGHS NSSPRHSEAA TAQREEWKMF IGGLSWDTTK KDLKDYFSKF GEVVDCTLKL DPITGRSRGF GFVLFKESES VDKVMDQKEH KLNGKVIDPK RAKAMKTKEP VKKIFVGGLS PDTPEEKIRE YFGGFGEVES IELPMDNKTN KRRGFCFITF KEEEPVKKIM EKKYHNVGLS KCEIKVAMSK EQYQQQQQWG SRGGFAGRAR GRGGDQQSGY GKVSRRGGHQ NSYKPYPositive Samples: HeLa, Jurkat, HepG2, Mouse brain, Rat brain
Cellular Location: Cytoplasm, Nucleus
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). hnRNPs are nucleic acid-binding proteins that complex with heterogeneous nuclear RNA (hnRNA). They are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and mRNA metabolism and transport.
The hnRNP D protein has two quasi-RRM domains that bind RNAs and localizes to both the nucleus and cytoplasm. It is involved in the regulation of mRNA stability. Alternative splicing results in four transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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