Thermo Fisher Scientific Hemoglobin Monoclonal Antibody (HB11-231.2)
인간 헤모글로빈에 특이적인 단클론 항체로, ELISA 및 Western blot에 적합합니다. Mouse IgG1 형이며, Protein G로 정제된 액상 형태입니다. 보존제가 없으며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HB11-231.2 |
| Immunogen | Purified human hemoglobin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075034 |
Product Specific Information
MA1-10808 detects hemoglobin from human samples.
This antibody does not detect bovine, chicken, equine, ovine, or porcine hemoglobin.
MA1-10808 has been successfully used in ELISA and Western blot applications.
The immunogen is purified human hemoglobin.
Target Information
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci:
5′- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3′.
The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical, differing slightly in untranslated regions and introns, but significantly in 3′ untranslated regions.
Two alpha chains plus two beta chains constitute HbA, which comprises about 97% of adult hemoglobin.
Alpha chains combine with delta chains to form HbA2, which with HbF (fetal hemoglobin) makes up the remaining 3%.
Alpha thalassemias result from deletions of one or both alpha genes (HBA2 and HBA1), though nondeletion variants are also known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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