
Thermo Fisher Scientific PSMD12 Polyclonal Antibody
Rabbit polyclonal antibody against human PSMD12, validated for Western blot. Recognizes N-terminal region (aa 1–50). High purity via affinity chromatography. Supplied as liquid in PBS with sucrose and sodium azide. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PSMD12 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610540 |
Product Specific Information
Peptide sequence:
MADGGSERAD GRIVKMEVDY SATVDQRLPE CAKLAKEGRL QEVIETLLSL
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
Target Information
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is part of several histone deacetylase complexes, including the mSin3 co-repressor complex, and participates in chromatin assembly. It can interact with the BRCA1 tumor-suppressor gene and may play a role in regulating cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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