Thermo Fisher Scientific PER3 Polyclonal Antibody
PER3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 사람 시료에 반응합니다. Western blot에 최적화되어 있으며, 합성 펩타이드 면역원 기반으로 제작되었습니다. 액상 형태, 0.5 mg/mL 농도, -20°C 보관 조건.
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Applications
- Western Blot (WB)
Tested Dilution: 1 µg/mL
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human PER3 (aa 647–696) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608450 |
Product Specific Information
Peptide sequence:
DATLFCEPWT LNMQPAPLTS EEFKHVGLTA AVLSAHTQKE EQNYVDKFRE
Sequence homology:
- Dog: 100%
- Horse: 100%
- Human: 100%
- Mouse: 93%
- Pig: 86%
- Rat: 93%
- Sheep: 86%
- Zebrafish: 79%
Target Information
The PER3 gene belongs to the Period family and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. It encodes components of circadian rhythms related to locomotor activity, metabolism, and behavior.
PER3 is upregulated by CLOCK/ARNTL heterodimers and represses this upregulation via a feedback loop involving PER/CRY heterodimers.
Polymorphisms in PER3 have been associated with sleep disorders. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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